| | 1 | = Minutes RNA-Seq Analysis group (2014-06-24 15:00-16:00) = |
| | 2 | |
| | 3 | * Peter-Bram 't Hoen (LUMC) (Chair) |
| | 4 | * Jeroen van Rooij (EMC) (Minutes) |
| | 5 | * Martijn Vermaat (LUMC) |
| | 6 | * Maarten van Iterson (LUMC) |
| | 7 | * Lude Franke (UMCG) |
| | 8 | * Dasha Zhenarkova (UMCG) |
| | 9 | * Patrick Deelen (UMCG) |
| | 10 | * Freerk van Dijk (UMCG) |
| | 11 | |
| | 12 | == Data Production == |
| | 13 | Now more than 4000 samples sequenced, are being uploaded to grid. (Jeroen) |
| | 14 | |
| | 15 | == Processing Through Pipeline == |
| | 16 | Some NTR samples didn't pass through pipeline (Maarten) |
| | 17 | |
| | 18 | === QTLs === |
| | 19 | Dasha emailed an update on the eQTL analysis on GEUVADIS data (replicating BIOS hits, 34% replicated (9% opposite effect)) |
| | 20 | Might be that the non-replicated eQTLs are those that are lowly expressed. |
| | 21 | We also discussed looking into the opposite allelic effects, this will be followed up. |
| | 22 | |
| | 23 | == Round of updates == |
| | 24 | Lude attended a Gtex meeting, papers not yet submitted, will be done soon. There were no very unexpected results or analysis presented. |
| | 25 | Dasha transferred NTR genotyes to VM, available there now. |
| | 26 | |
| | 27 | PolyA QTL mapping on GEUVADIS dataset, results available on VM, might be rerun with different settings based on BIOS dataset. |
| | 28 | |
| | 29 | Exon-Ratio QTLs was run by Martijn, gather some descriptive statistics. |
| | 30 | |
| | 31 | ''' __Next call, July 1st at 3pm hosted by Michiel __ ''' |
