|   | 1 |  ==BBMRI omics Hands-on Course=== | 
                  
                          |   | 2 |  | 
                  
                          |   | 3 | date: March 31, 2017 | 
                  
                          |   | 4 | Location: SURFsara, Utrech  | 
                  
                          |   | 5 | url: https://www.bbmri.nl/event/bbmri-omics-introduction-and-hands-on-application/=== | 
                  
                          |   | 6 |  | 
                  
                          |   | 7 | ==Program==: | 
                  
                          |   | 8 |  | 
                  
                          |   | 9 | 10:00-10:30 Introduction to available omics data within BBMRI-omics.nl. Description of RNA-seq, 450k methylation, metabolomics, imputed genotypes, phenotypes and technical covariates. Data location and access. (Rick Jansen) | 
                  
                          |   | 10 |  | 
                  
                          |   | 11 | 10.30-11.15: Introduction to R package BIOSRutils. How to use BIOSRutils for filtering and QC, and finally run EWAS and TWAS (Maarten van Iterson) | 
                  
                          |   | 12 |  | 
                  
                          |   | 13 | 11.15-12.15: Practicum (Maarten van Iterson)  | 
                  
                          |   | 14 |  | 
                  
                          |   | 15 | 12.15-13.15: Lunch (demo: using BBMRI-Omics.nl online atlases (Jan-Bert van Klinken)) | 
                  
                          |   | 16 |  | 
                  
                          |   | 17 | 13.15-13.45: Joost Verlouw: QTL lookup of GWAS hits. Take the SNP hits from a recent GWAS, extract corresponding BIOS genotype data, run association with full Methylation, Expression and Metabolomics data sets. | 
                  
                          |   | 18 |  | 
                  
                          |   | 19 | 13.45-14.45: Practicum (Joost Verlouw) | 
                  
                          |   | 20 |  | 
                  
                          |   | 21 | 14.45-15.15- Tea break | 
                  
                          |   | 22 |  | 
                  
                          |   | 23 | 15:15-15:45: Introduction to the Brainshake 1H-NMR metabolomics platform (Marian Beekman) | 
                  
                          |   | 24 |  | 
                  
                          |   | 25 | 15:45-16.30: Practicum. Analyzing Metabolomics data (Koen Dekker) | 
                  
                          |   | 26 |  | 
                  
                          |   | 27 | 16:30-17:00: Allele specific expression (Niek de Klein/Freerk van Dijk) | 
                  
                          |   | 28 | 17:00-17:45: Practicum (Niek de Klein/Freerk van Dijk)) | 
                  
                          |   | 29 |  | 
                  
                          |   | 30 | 18:00 Drinks | 
                  
                          |   | 31 |  | 
                  
                          |   | 32 | ==Practicum guidelines and exercises== | 
                  
                          |   | 33 |  |