|   | 1 | = Phenotype data and metadata = | 
                  
                          |   | 2 | This file contains data on the core phenotypes, data on DNA/RNA samples and measurements (meta-data) and agreement that samples and data are made available to analyses within RP3. | 
                  
                          |   | 3 |  | 
                  
                          |   | 4 | == Format == | 
                  
                          |   | 5 |  ||Biobank  || CODAM, LL, LLS, NTR, PAN, RS || | 
                  
                          |   | 6 |  ||pheno_id  || ID linked to phenotypic data in line with sample_id list provided [[BR]] for data uploads (can be person_id if no special id for phenotype exists) || | 
                  
                          |   | 7 |  ||Ascertainment_criterion  || Inclusion criterion biobank/selected samples || | 
                  
                          |   | 8 |  ||GWAS_Chip  || comma separated in case of multiple chips || | 
                  
                          |   | 9 |  ||GWAS_DataGeneration_Date  || YYYY || | 
                  
                          |   | 10 |  ||DNA_BloodSampling_Age  || xx.x (i.e. years + 1 decimal) || | 
                  
                          |   | 11 |  ||DNA_BloodSampling_Date  || YYYY-MM-DD || | 
                  
                          |   | 12 |  ||DNA_BloodSampling_Time  || HH:MM || | 
                  
                          |   | 13 |  ||DNA_Source  || Whole blood, other || | 
                  
                          |   | 14 |  ||DNA_Extraction_Method  ||   || | 
                  
                          |   | 15 |  ||DNA_Extraction_Date  || YYYY-MM-DD || | 
                  
                          |   | 16 |  ||DNA_QuantificationMethod  ||   || | 
                  
                          |   | 17 |  ||DNA_A260A280ratio  || A260/A280 || | 
                  
                          |   | 18 |  ||RNA_BloodSampling_Age  || xx.x (i.e. years + 1 decimal) || | 
                  
                          |   | 19 |  ||RNA_Sampling_Date  || YYYY-MM-DD || | 
                  
                          |   | 20 |  ||RNA_Sampling_Time  || HH:MM || | 
                  
                          |   | 21 |  ||RNA_Source  || Pax gene, other || | 
                  
                          |   | 22 |  ||RNA_Extraction_Date  || YYYY-MM-DD || | 
                  
                          |   | 23 |  ||RNA_Extraction_Method  ||   || | 
                  
                          |   | 24 |  ||RNA_RIN  || RIN or equivalent score || | 
                  
                          |   | 25 |  ||RNA_A260280ratio  || A260/A280 || | 
                  
                          |   | 26 |  ||!BirthYear  || xxxx (e.g. 1969) || | 
                  
                          |   | 27 |  ||Sex  || 0=male/1=female || | 
                  
                          |   | 28 |  ||Smoking_Age  || xx.x (i.e. years + 1 decimal) || | 
                  
                          |   | 29 |  ||Smoking  || 0=non-smoker/1=former smoker/2=current smoker || | 
                  
                          |   | 30 |  ||Lipids_BloodSampling_Age  || xx.x (i.e. years + 1 decimal) || | 
                  
                          |   | 31 |  ||Lipids_BloodSampling_Date  || DD/MM/YYYY || | 
                  
                          |   | 32 |  ||Lipids_BloodSampling_Time  || HH:MM || | 
                  
                          |   | 33 |  ||Lipids_BloodSampling_Fasting  || 0=no/1=yes || | 
                  
                          |   | 34 |  ||!TotChol  || in mmol/L || | 
                  
                          |   | 35 |  ||HDLchol  || in mmol/L || | 
                  
                          |   | 36 |  ||Triglycerides  || in mmol/L || | 
                  
                          |   | 37 |  ||LDLchol  || in mmol/L || | 
                  
                          |   | 38 |  ||LDLcholMethod  || 1=Friedewald estimation/2=measured || | 
                  
                          |   | 39 |  ||LipidsMed_Age  || xx.x (i.e. years + 1 decimal) || | 
                  
                          |   | 40 |  ||!LipidMed  || 0=no/1=statins/2=yes, but no statins || | 
                  
                          |   | 41 |  ||Anthropometry_Age  || xx.x (i.e. years + 1 decimal) || | 
                  
                          |   | 42 |  ||Height  || xxx.x in cm || | 
                  
                          |   | 43 |  ||Weight  || xx.x in kg || | 
                  
                          |   | 44 |  ||CRP_BloodSampling_Age  || xx.x (i.e. years + 1 decimal) || | 
                  
                          |   | 45 |  ||CRP_BloodSampling_Date  || YYYY-MM-DD || | 
                  
                          |   | 46 |  ||CRP_BloodSampling_Time  || HH:MM || | 
                  
                          |   | 47 |  ||hsCRP  || in mg/L || | 
                  
                          |   | 48 |  ||CellCount_BloodSampling_Age  || xx.x (i.e. years + 1 decimal) || | 
                  
                          |   | 49 |  ||CellCount_BloodSampling_Date  || YYYY-MM-DD || | 
                  
                          |   | 50 |  ||CellCount_BloodSampling_Time  || HH:MM || | 
                  
                          |   | 51 |  ||WBC  || WhiteBloodcellCount_WBC in x10^9cells/L || | 
                  
                          |   | 52 |  ||RBC  || !RedBloodcellCount in x10^12cells/L || | 
                  
                          |   | 53 |  ||HGB  || Hemoglobulin in mmol/L || | 
                  
                          |   | 54 |  ||HCT  || Hematocrit L/L || | 
                  
                          |   | 55 |  ||MCV  || !MeanCorpuscularVolume in fL || | 
                  
                          |   | 56 |  ||MCH  || !MeanCorpuscularHemoglobin fmol || | 
                  
                          |   | 57 |  ||MCHC  || !MeanCorpuscularHemoglobinConcentration in mmol/L || | 
                  
                          |   | 58 |  ||CHCM  || !CorpuscularHemoglobinConcentrationMean in mmol/L || | 
                  
                          |   | 59 |  ||CH  || !CorpuscularHemoglobinContent in fmol/L || | 
                  
                          |   | 60 |  ||RDW  || !RedCellVolumeDistributionWidth in % || | 
                  
                          |   | 61 |  ||HDW  || !HemoglobinConcentrationDistributionWidth in mmol/L || | 
                  
                          |   | 62 |  ||PLT  || !PlateletCount in x10^9cells/L || | 
                  
                          |   | 63 |  ||MPV  || !MeanPlateletVolume in fL || | 
                  
                          |   | 64 |  ||Neut  || !NeutrophilCount in 10^9/L || | 
                  
                          |   | 65 |  ||Lymph  || !LymphocyteCount in 10^9/L || | 
                  
                          |   | 66 |  ||Mono  || !MonocyteCount in 10^9/L || | 
                  
                          |   | 67 |  ||Eos  || !EosinophilCount in 10^9/L || | 
                  
                          |   | 68 |  ||Baso  || !BasophilCount in 10^9/L || | 
                  
                          |   | 69 |  ||LUC  || !LargeUnstainedCells in 10^9/L || | 
                  
                          |   | 70 |  ||Neut_Perc  || in % of white bloodcell count || | 
                  
                          |   | 71 |  ||Lymph_Perc  || in % of white bloodcell count || | 
                  
                          |   | 72 |  ||Mono_Perc  || in % of white bloodcell count || | 
                  
                          |   | 73 |  ||Eos_Perc  || in % of white bloodcell count || | 
                  
                          |   | 74 |  ||Baso_Perc  || in % of white bloodcell count || | 
                  
                          |   | 75 |  ||LUC_Perc  || in % of white bloodcell count || | 
                  
                          |   | 76 |   | 
                  
                          |   | 77 | == Data == | 
                  
                          |   | 78 |  | 
                  
                          |   | 79 | === V02 === | 
                  
                          |   | 80 | * Corrected smoking age of 0 for non smoking sample | 
                  
                          |   | 81 | * Added unique id <biobank>-<biobankSampleId> | 
                  
                          |   | 82 |  | 
                  
                          |   | 83 | attachment:RP3_pheno_V02.txt | 
                  
                          |   | 84 |  | 
                  
                          |   | 85 | === V01 === | 
                  
                          |   | 86 | The complete table with all phenotype data can be found here: attachment:RP3_pheno_V01.txt | 
                  
                          |   | 87 |  | 
                  
                          |   | 88 | Comparative plots have been generated and can be downloaded here: attachment:RP3_pheno_V01_plots.pdf | 
                  
                          |   | 89 |  | 
                  
                          |   | 90 | == File name == | 
                  
                          |   | 91 | All phenotype data is stored at srm://srm.grid.sara.nl/pnfs/grid.sara.nl/data/bbmri.nl/RP3/<biobank>/Phenotypes: | 
                  
                          |   | 92 | {{{ | 
                  
                          |   | 93 | <biobank>-phen-<YYYYMMDD>.txt | 
                  
                          |   | 94 | }}} |